Cover Feature: Live Monitoring of Anionic Living Polymerizations by Electrospray‐Ionization Mass Spectrometry (Chem. Eur. J. 13/2023)
نویسندگان
چکیده
Electrospray-ionization mass spectrometry easily distinguishes the different living oligomers resulting from anionic ring-opening polymerization of acceptor-substituted cyclopropane Mcyclic. Kinetic modeling reproduces measured time evolution growing and affords rate constants individual propagation steps. More information can be found in Research Article by N. F. Eisele, M. Peters, K. Koszinowski (DOI: 10.1002/chem.202203762).
منابع مشابه
Live single-cell mass spectrometry.
The history from bio-imaging to live single-cell mass spectrometry (MS) is herein reviewed. The limitation of the current bio-imaging method is probing only known molecules, and a method for finding new molecules is needed for cells which, however, show individual behaviors even in the same incubation dish. Single-cell MALDI-TOF/MS has been developed, but it can detect only molecules that can b...
متن کاملIn Vivo and Real-time Monitoring of Secondary Metabolites of Living Organisms by Mass Spectrometry
Secondary metabolites are compounds that are important for the survival and propagation of animals and plants. Our current understanding on the roles and secretion mechanism of secondary metabolites is limited by the existing techniques that typically cannot provide transient and dynamic information about the metabolic processes. In this manuscript, by detecting venoms secreted by living scorpi...
متن کاملDirect drug metabolism monitoring in a live single hepatic cell by video mass spectrometry.
The metabolism of anti-breast cancer drug, tamoxifen, in a single human hepatocellular carcinoma cell, HepG2, was directly monitored by a video-mass spectroscope. The cytoplasm, a vacuole or nucleus of the cell was directly sucked by a nano-spray tip under a video-microscope, and then was introduced into a mass spectrometer. Unchanged drug molecules were found in cytoplasm and a vacuole, but ...
متن کاملLive Single-Cell Plant Hormone Analysis by Video-Mass Spectrometry.
Studies have indicated that endogenous concentrations of plant hormones are regulated very locally within plants. To understand the mechanisms underlying hormone-mediated physiological processes, it is indispensable to know the exact hormone concentrations at cellular levels. In the present study, we established a system to determine levels of ABA and jasmonoyl-isoleucine (JA-Ile) from single c...
متن کاملLive single-cell molecular analysis by video-mass spectrometry.
The direct molecular analysis of a live single cell viewed under a video-microscope has been developed. The cell contents are sucked into a nano-electrospray tip, and hundreds of peaks of ionic compounds of low molecular weight are detected by nano-ESI Q-TOF mass spectrometry (MS). Cell-specific MS peaks in a single mouse-embryonic fibroblasts cell are extracted by a t-test, and one of the peak...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemistry: A European Journal
سال: 2023
ISSN: ['0947-6539', '1521-3765']
DOI: https://doi.org/10.1002/chem.202300363